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- サプライヤー
- TargteMol
- カタログNo.
- TMPY-02726
- 製品名称
- RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (hFc)
- タンパク質名
- RANKL/TNFSF11/CD254
- Species
- Mouse
- HOST
- HEK293 Cells
- 50μg: -
- お問い合わせ
Overview
| Synonyms | RANKL, OPGL, Trance, OPG, tumor necrosis factor (ligand) superfamily, member 11, ODF, Ly109l |
|---|---|
| Characteristics | Immobilized mouse Fc-TNFSF11 at 10 μg/ml (100 μl/well) can bind biotinylated human TNFRSF11B-His , The EC50 of biotinylated human TNFRSF11B-His is 0.07-0.17 μg/ml. |
| Endotoxin Level | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Purity | 97% |
| Description | RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56 kDa and the accession number is AAC40113.1. |
| Reference | Nakashima T,et al.(2003) RANKL and RANK as novel therapeutic targets for arthritis. Curr Opin Rheumatol. 15(3): 280-7.,Schwarz EM,et al.(2007) Clinical development of anti-RANKL therapy. Arthritis Res Ther. 9 Suppl 1: S7.,Takayanagi H,et al.(2002) Signaling crosstalk between RANKL and interferons in osteoclast differentiation. Arthritis Res. 4 Suppl 3: S227-32.,Leibbrandt A,et al.(2008) RANK/RANKL: regulators of immune responses and bone physiology. Ann N Y Acad Sci. 1143: 123-50. |
| URL | https://www.targetmol.com/recombinant-protein/rankl_protein_mouse_recombinant_hfc_tag_ |
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