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- サプライヤー
- TargteMol
- カタログNo.
- TMPY-02592
- 製品名称
- Annexin VI/ANXA6 Protein, Human, Recombinant (His)
- タンパク質名
- Annexin VI/ANXA6
- Species
- Human
- HOST
- E. coli
- 100μg: -
- お問い合わせ
Overview
| Synonyms | ANX6, annexin A6, CBP68 |
|---|---|
| Characteristics | Measured by its ability to bind human CD21-His in functional Elisa. |
| Endotoxin Level | Please contact us for more information. |
| Purity | > 97 % as determined by SDS-PAGE |
| Description | Annexin A6, also known as ANXA6 or ANXAⅥ, belongs to a family of Ca2+-dependent membrane and phospholipid binding proteins. Members of this family have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 6 is phosphorylated in vivo associated with cell growth. Annexin 6 was not phosphorylated in quiescent cells, but was phosphorylated on serine and to a lesser extent threonine, several hours following cell stimulation. Experiment has revealed the presence of annexin A6 on the cell surface of variety cells as putative receptors and / or binding proteins for chondroitin sulfate proteoglycans, helping cells to bind with this extracellular matrix glycosaminoglycan chondroitin sulfate which is related to the cell-substratum adhesion. A post-tranlational modification other than direct protein phosphorylation may influence the activity of annexin6 and provide evidence linking cell growth with regulation of annexin 6 function. |
| Reference | Moss SE,et al. (1992) A growth-dependent post-translational modification of annexin VI. Biochim Biophys Acta. 1160 (1): 120-6.,Song G,et al. (1998) Altered cardiac annexin mRNA and protein levels in the left ventricle of patients with end-stage heart failure. J Mol Cell Cardio. 30 (3): 443-51.,Takagi H,et al. (2002) Annexin 6 is a putative cell surface receptor for chondroitin sulfate chains. J Cell Sci. 115 (16): 3309-18. |
| URL | https://www.targetmol.com/recombinant-protein/annexin_vi_anxa6_protein_human_recombinant_his_tag_ |
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