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- サプライヤー
- TargteMol
- カタログNo.
- TMPY-02580
- 製品名称
- Histone H1 Protein, Human, Recombinant (His)
- タンパク質名
- Histone H1
- Species
- Human
- HOST
- E. coli
- 100μg: -
- お問い合わせ
Overview
| Synonyms | HSP60, HSP65, CPN60, H1 histone family, member 0, H10, HLD4, HSPD1, HuCHA60, H1FV, SPG13, GROEL |
|---|---|
| Characteristics | Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Endotoxin Level | Please contact us for more information. |
| Purity | 95.90% |
| Description | H1 histone family, member 0 (H1F0) is a member of the H1 histone family of nuclear proteins which are a component of chromatin in eukaryotic cells. It's involved in maintaining the structure of chromatin by packing the "beads on a string" sub-structure into a high order structure. The lysine-rich H1 histone family in mammals includes eleven members. In higher eukaryotes, all H1 variants have the same general structure, consisting of a central conserved globular domain and less conserved N-terminal and C-terminal tails. These tails are moderately conserved among species, but differ among variants, suggesting a specific function for each H1 variant. Studies on the role of particular subtypes at specific developmental stages in lower eukaryotes, but also in vertebrates suggest that specific subtypes of H1 participate in particular systems of gene regulation. |
| Reference | Ramakrishnan V,et al. (1993) Crystal structure of globular domain of histone H5 and its implications for nucleosome binding. Nature. 362 (6417): 219-23.,Happel N,et al. (2009) Histone H1 and its isoforms: contribution to chromatin structure and function. Gene. 431 (1-2): 1-12.,Izzo A,et al. (2008) The histone H1 family: specific members, specific functions. Biol Chem. 389 (4): 333-43. |
| URL | https://www.targetmol.com/recombinant-protein/histone_h1_protein_human_recombinant_his_tag_hplc_verified |
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