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- サプライヤー
- TargteMol
- カタログNo.
- TMPY-02535
- 製品名称
- TNFR1/CD120a/TNFRSF1A Protein, Mouse, Recombinant (hFc)
- タンパク質名
- TNFR1/CD120a/TNFRSF1A
- Species
- Mouse
- HOST
- HEK293 Cells
- 100μg: -
- お問い合わせ
Overview
| Synonyms | TNFalpha-R1, TNF-R, TNFRp55, TNFAR, TNF-R-I, FPF, TNF-R55, TNFR60, TNFRI, tumor necrosis factor receptor superfamily member 1A, Tnfr-2, TNF-R1, TNF-αR1, Tnfr1, CD120a, TNF-alphaR1, p55, TNFα-R1, p55-R |
|---|---|
| Characteristics | 1. Measured by its binding ability in a functional ELISA. Immobilized Mouse TNF-alpha at 2 μg/ml (100 μl/well) can bind Mouse TNFRSF1AhFc , the EC50 of Mouse TNFRSF1AhFc is 1.5-9.0 ng/mL. 2. Measured by its ability to inhibit the TNFα-mediated cytotoxicity in the L-929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D. The ED50 for this effect is typically 15-65 ng/mL in the presence of 0.1 ng/mL of recombinant mouse TNFα. |
| Endotoxin Level | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Purity | 94% |
| Description | TNFR1/CD120a/TNFRSF1A Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 47.4 kDa and the accession number is P25118. |
| Reference | Matesanz-Isabel J,et al.(2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.,Ho IC,et al.(2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.,Cottin V,et al.(2002) Restricted localization of the TNF receptor CD120a to lipid rafts: a novel role for the death domain. The journal of immunology. 168: 4095-102.,Zola H,et al.(2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5. |
| URL | https://www.targetmol.com/recombinant-protein/tnfr1_cd120a_protein_mouse_recombinant_hfc_tag_ |
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