HER3/ERBB3 Protein, Mouse, Recombinant (His) [TMPY-02365]

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Synonyms	Erbb-3r, Erbb3r, erb-b2 receptor tyrosine kinase 3, C76256, Erbb-3, Her3, Erbb3
Characteristics	Measured by its binding ability in a functional ELISA.1. Immobilized mouse ErbB3-His at 10 μg/ml (100 μl/well) can bind biotinylated human NRG1 (isoform Beta1) with a linear range of 0.018-0.125 μg/ml.2. Immobilized mouse ErbB3-His at 10 μg/ml (100 μl/well) can bind biotinylated human NRG1 (aa 2-246)-Fc with a linear range of 6.25-100 ng/ml.
Endotoxin Level	< 1.0 EU/μg of the protein as determined by the LAL method.
Purity	97.10%
Description	HER3/ERBB3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 70 kDa and the accession number is Q61526.
Reference	Plowman G.D.,et al., (1990), Molecular cloning and expression of an additional epidermal growth factor receptor-related gene.Proc. Natl. Acad. Sci. U.S.A. 87:4905-4909.,Katoh M.,et al.,(1993), c-erbB3 gene encodes secreted as well as transmembrane receptor tyrosine kinase.Biochem. Biophys. Res. Commun. 192:1189-1197.,Kraus M.H.,et al.,(1989), Isolation and characterization of ERBB3, a third member of the ERBB/epidermal growth factor receptor family: evidence for overexpression in a subset of human mammary tumors. Proc. Natl. Acad. Sci. U.S.A. 86:9193-9197.
URL	https://www.targetmol.com/recombinant-protein/her3_erbb3_protein_mouse_recombinant_his_tag_

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