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- サプライヤー
- TargteMol
- カタログNo.
- TMPY-02361
- 製品名称
- VEGFR2/KDR Protein, Human, Recombinant (His)
- タンパク質名
- VEGFR2/KDR
- Species
- Human
- HOST
- HEK293 Cells
- 100μg: -
- お問い合わせ
Overview
| Synonyms | VEGFR2, kinase insert domain receptor, VEGFR, FLK1, Flk-1, CD309 |
|---|---|
| Characteristics | 1. Measured by its ability to inhibit the VEGF-dependent proliferation of human umbilical vein endothelial cells (HUVEC). The ED50 for this effect is typically 10-50 μg/mL in the presence of 10 ng/mL recombinant human VEGF165.<br> 2. Using the Octet RED System, the affinity constant (Kd) of VEGFR2/KDR Protein, Human, Recombinant (His Tag) bound to Anti-VEGFR2 Antibody was 1.9 nM. |
| Endotoxin Level | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Purity | 95.90% |
| Description | VEGFR2/KDR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 84.6 kDa and the accession number is P35968-1. |
| Reference | Shibuya M. (2006) Vascular endothelial growth factor (VEGF)-Receptor2: its biological functions, major signaling pathway, and specific ligand VEGF-E. Endothelium. 13(2): 63-9.,Marwick JA,et al.(2010) Cigarette smoke regulates VEGFR2-mediated survival signaling in rat lungs. J Inflamm (Lond). 7(1): 11.,Bruns AF,et al.(2010) Ligand-stimulated VEGFR2 signaling is regulated by co-ordinated trafficking and proteolysis. Traffic. 11(1): 161-74. |
| URL | https://www.targetmol.com/recombinant-protein/vegfr2_kdr_protein_human_recombinant_ecd_his_tag_hplc_verified |
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