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- サプライヤー
- TargteMol
- カタログNo.
- TMPY-02292
- 製品名称
- IGSF11 Protein, Human, Recombinant (His)
- タンパク質名
- IGSF11
- Species
- Human
- HOST
- HEK293 Cells
- 20μg: -
- お問い合わせ
Overview
| Synonyms | CT119, immunoglobulin superfamily, member 11, BT-IgSF, Igsf13, CXADRL1, VSIG3 |
|---|---|
| Characteristics | Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Endotoxin Level | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Purity | SDS-PAGE: 96.2%; SEC-HPLC: 90.3% |
| Description | Immunoglobulin superfamily member 11(IGSF11) is expressed on the plasma membrane in the testis and brain. These IGSF proteins undergo final modifications during capacitation and/or the acrosome reaction. IGSF proteins share significant homology with endothelial cell-selective adhesion molecule and coxsackievirus and adenovirus receptor, which mediates cell attachment and homotypic intercellular interactions. In clinical, the IGSF11 has been reported to overexpressed in colorectal cancers and hepatocellular carcinomas, as well as intestinal-type gastric cancers, compared to their corresponding non-cancerous tissues. The IGSF11 has also been found expressed abundantly in the testis and ovary and the IGSF11 can be used as a candidate of cancer-testis antigen. |
| Reference | Toshimori K,et al.(2006) The involvement of immunoglobulin superfamily proteins in spermatogenesis and sperm-egg interaction. Reproductive Medicine and Biology. 5(2): 87-93.,Watanabe T,et al.(2005) Identification of immunoglobulin superfamily 11 (IGSF11) as a novel target for cancer immunotherapy of gastrointestinal and hepatocellular carcinomas. Cancer Science. 96(8) :498-506.,Coyne CB,et al.(2005) CAR: A virus receptor within the tight junction. Advanced Drug Delivery Reviews. 57(6) : 869-82. |
| URL | https://www.targetmol.com/recombinant-protein/igsf11_protein_human_recombinant_his_tag_hplc_verified |
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