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- サプライヤー
- TargteMol
- カタログNo.
- TMPY-02287
- 製品名称
- Ku70 & Ku80 Heterodimer Protein, Human, Recombinant (His)
- タンパク質名
- Ku70 & Ku80 Heterodimer
- Species
- Human
- HOST
- Baculovirus Insect Cells
- 50μg: -
- お問い合わせ
Overview
| Synonyms | KARP1, XRCC5 & XRCC6, KUB2, KU80, KARP-1, Ku86, NFIV |
|---|---|
| Characteristics | Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Endotoxin Level | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Purity | 94.70% |
| Description | X-ray repair cross-complementing protein 5, also known as 86 kDa subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 2, ATP-dependent DNA helicase II 8 kDa subunit, CTC box-binding factor 85 kDa subunit, DNA repair protein XRCC5, Lupus Ku autoantigen protein p86, TLAA and XRCC5, is a nucleus and chromosome which belongs to the ku8 family. XRCC5 is a single-stranded DNA-dependent ATP-dependent helicase. XRCC5 has a role in chromosome translocation. X-ray repair cross-complementing protein 6, also known as 5'-deoxyribose-5-phosphate lyase Ku7, ATP-dependent DNA helicase 2 subunit 1, ATP-dependent DNA helicase II 7 kDa subunit, 7 kDa subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 1, CTC box-binding factor 75 kDa subunit, Lupus Ku autoantigen protein p7, Thyroid-lupus autoantigen and XRCC6, is a nucleus and chromosome which belongs to the ku7 family. Heterodimer of a XRCC6 and a XRCC5 subunit associates in a DNA-dependent manner with PRKDC to form the DNA-dependent protein kinase complex DNA-PK, and with the LIG4-XRCC4 complex. The dimer also associates with NAA15, and this complex binds to the osteocalcin promoter and activates osteocalcin expression. |
| Reference | Featherstone C. et al., 1999, Mutat Res. 434: 3-15.,Roberts SA. et al., 2010, Nature. 464:1214-7.,Zhang Z. et al., 2001, J Biol Chem. 276: 38231-6.,Hsu H-L. et al.,? 2002, DNA Repai.r 1: 225-35.,Burkard TR. et al., 2011, BMC Syst Biol. 5: 17. |
| URL | https://www.targetmol.com/recombinant-protein/ku70_ku80_heterodimer_protein_human_recombinant_his_tag_ |
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