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- サプライヤー
- TargteMol
- カタログNo.
- TMPY-02279
- 製品名称
- Nucleoside phosphorylase/PNP Protein, Human, Recombinant (His)
- タンパク質名
- Nucleoside phosphorylase/PNP
- Species
- Human
- HOST
- E. coli
- 50μg: -
- お問い合わせ
Overview
| Synonyms | PUNP, PRO1837, purine nucleoside phosphorylase, NP |
|---|---|
| Characteristics | Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Endotoxin Level | Please contact us for more information. |
| Purity | SDS-PAGE: > 97% |
| Description | Purine nucleoside phosphorylase (PNP) is a purine-metabolizing enzyme that catalyzes the reversible phosphorolysis of 6-oxypurine (deoxy)nucleosides to their respective bases and (deoxy)ribose-1-phosphate. It is a key enzyme in the purine salvage pathway of mammalian cells. Purine nucleoside phosphorylase is a transferase that catalyzes the addition of phosphate and removal of a purine base from guanosine and similar nucleosides.PNP defects result in metabolic abnormalities and fatal T cell immunodeficiency. Purine nucleoside phosphorylase (PNP) is a target for leukemia, gout, and autoimmune disorders. |
| Reference | de Azevedo,W.F.?et al., 2003, Biochem Biophys Res Commun. 312 (3): 767-72.,Perera,G.K. et al., 2005,Clin Exp Dermatol. 30?(1):27-9.,Canduri,F. et al., 2005,?Acta Crystallogr D Biol Crystallogr. 61?(Pt 7): 856-62. |
| URL | https://www.targetmol.com/recombinant-protein/nucleoside_phosphorylase_pnp_protein_human_recombinant_his_tag_ |
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