IL-24 Protein, Human, Recombinant (His) [TMPY-02087]

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Synonyms	C49A, IL10B, MOB5, ST16, MDA7, FISP, interleukin 24
Characteristics	Measured in a cell proliferation assay using BaF3 mouse pro-B cells transfected with human IL?20 Rα and human IL?20 Rβ. The EC50 for this effect is typically 0.05-0.25 ng/mL.
Endotoxin Level	< 1.0 EU/μg of the protein as determined by the LAL method.
Purity	95.40%
Description	IL-24 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.5 kDa and the accession number is A0A7R8C2Y5.
Reference	Sarkar D,et al.. (2002) mda-7 (IL-24) Mediates selective apoptosis in human melanoma cells by inducing the coordinated overexpression of the GADD family of genes by means of p38 MAPK. Proc Natl Acad Sci U S A. 99(15): 10054-9.,Sauane M,et al.. (2003) MDA-7/IL-24: novel cancer growth suppressing and apoptosis inducing cytokine. Cytokine Growth Factor Rev. 14(1): 35-51.,Wang M,et al.. (2002) Interleukin 24 (MDA-7/MOB-5) signals through two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2. J Biol Chem. 277(9): 7341-7.
URL	https://www.targetmol.com/recombinant-protein/il24_protein_human_recombinant_his_tag_

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