MICA Protein, Human, Recombinant (His), MICA*018 [TMPY-02053]

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Synonyms	MGC21250, MIC-A, MGC111087, FLJ36918, FLJ60820, DAMA-345G11.2, MHC class I polypeptide-related sequence A, PERB11.1
Characteristics	Measured by its binding ability in a functional ELISA.?Immobilized MICAh at 2 μg/mL (100 μL/well) can bind S4-Fc3L3-NKG2D , the EC50 of S4-Fc3L3-NKG2D is 120-300 ng/mL.
Endotoxin Level	< 1.0 EU/μg of the protein as determined by the LAL method.
Purity	99.10%
Description	MICA Protein, Human, Recombinant (His), MICA*018 is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 34 kDa and the accession number is AAH16929.1.
Reference	Choy MK, et al. (2010) MICA polymorphism: biology and importance in immunity and disease. Trends Mol Med. 16(3): 97-106.,Bauer S, et al. (1999) Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA. Science. 285(5428): 727-9.,Mangham DC, et al. (2000) MICA-a highly sensitive and avidin-free immunohistochemical detection system. Adv Anat Pathol. 7(6): 360-4.,Li J, et al. (2005) Distinct pattern of human Vdelta1 gammadelta T cells recognizing MICA. Cell Mol Immunol. 2(4): 253-8.,Groh V, et al. (1998) Recognition of stress-induced MHC molecules by intestinal epithelial gammadelta T cells. Science. 279: 1737-40.
URL	https://www.targetmol.com/recombinant-protein/mica_protein_human_recombinant_ecd_his_tag_mica_018

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