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サプライヤー
TargteMol
カタログNo.
TMPY-02034
製品名称
Siglec-2/CD22 Protein, Human, Recombinant (His)
タンパク質名
Siglec-2/CD22
Species
Human
HOST
HEK293 Cells
100μg: -
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Overview

Synonyms CD22 molecule, SIGLEC2, SIGLEC-2
Characteristics Measured by its binding ability in a functional ELISA. Immobilized human CD22 at 0.02 μg/ml (100uL/well) can bind anti-human CD22 Mab with a linear range of 0.2-50 ng/ml.
Endotoxin Level < 1.0 EU/μg of the protein as determined by the LAL method.
Purity 97.60%
Description Siglec-2/CD22 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.6 kDa and the accession number is P20273-1.
Reference Walker JA,et al.(2008) CD22: an inhibitory enigma. Immunology. 123(3): 314-25.,Tedder TF,et al.(1997) CD22, a B lymphocyte-specific adhesion molecule that regulates antigen receptor signaling. Annu Rev Immunol. 15: 481-504.,Tedder TF,et al.(2005) CD22: a multifunctional receptor that regulates B lymphocyte survival and signal transduction. Adv Immunol. 88: 1-50.,Nitschke L. (2009) CD22 and Siglec-G: B-cell inhibitory receptors with distinct functions. Immunol Rev. 230(1): 128-43.,Fujimoto M,et al.(2007) B cell signaling and autoimmune diseases: CD19/CD22 loop as a B cell signaling device to regulate the balance of autoimmunity. J Dermatol Sci. 46(1): 1-9.
URL https://www.targetmol.com/recombinant-protein/cd22_protein_human_recombinant_ecd_his_tag_hplc_verified

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