c-Kit Protein, Human, Recombinant (His) [TMPY-01935]

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Synonyms	PBT, CD117, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, SCFR, C-Kit
Characteristics	Measured by its binding ability in a functional ELISA. Immobilized human KIT at 2 μg/mL (100 μl/well) can bind biotinylated Human KITL , The EC50 of biotinylated Human KITL is 2.0-9.0 ng/mL.
Endotoxin Level	< 1.0 EU/μg of the protein as determined by the LAL method.
Purity	99.40%
Description	c-Kit Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 56.7 kDa and the accession number is P10721-2.
Reference	Yarden Y, et al. (1987) Human proto-oncogene c-kit: a new cell surface receptor tyrosine kinase for an unidentified ligand. EMBO J. 6(11):3341-51.,Andre C, et al. (1997) Sequence analysis of two genomic regions containing the KIT and the FMS receptor tyrosine kinase genes. Genomics. 39(2):216-26.,McIntyre A, et al. (2005) Amplification and overexpression of the KIT gene is associated with progression in the seminoma subtype of testicular germ cell tumors of adolescents and adults. Cancer Res. 65(18):8085-9.,Leong KG, et al. (2008) Generation of a prostate from a single adult stem cell. Nature. 456(7223): 804-8.,Edling CE, et al. (2007) c-Kit--a hematopoietic cell essential receptor tyrosine kinase. Int J Biochem Cell Biol. 39(11):1995-8.
URL	https://www.targetmol.com/recombinant-protein/c_kit_protein_human_recombinant_ecd_his_tag_hplc_verified

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