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タンパク質、抗体、アッセイキット

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サプライヤー
TargteMol
カタログNo.
TMPY-01871
製品名称
IL-5R alpha/CD125 Protein, Human, Recombinant(aa 1-335, His)
タンパク質名
IL-5R alpha/CD125
Species
Human
HOST
HEK293 Cells
50μg: -
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Overview

Synonyms interleukin 5 receptor, alpha, IL5R, CD125, CDw125, HSIL5R3, interleukin 5 receptor, α
Characteristics 1. Measured by its binding ability in a functional ELISA.
2. Immobilized recombinant mouse IL5-his at 5 μg/mL (100 μL/well) can bind biotinylated human IL5Ra-his with a linear range of 32-4000 ng/mL.
3. Measured by its ability to inhibit IL5 dependent proliferation of TF1 human erythroleukemic cells. The ED50 for this effect is typically 0.7-2.8 μg/mL.
Endotoxin Level < 1.0 EU/μg of the protein as determined by the LAL method.
Purity 95.60%
Description IL-5R alpha/CD125 Protein, Human, Recombinant(aa 1-335, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.3 kDa and the accession number is Q01344-2.
Reference Cheong HS, et al. (2005) Association analysis of interleukin 5 receptor alpha subunit (IL5RA) polymorphisms and asthma. J Hum Genet. 50(12): 628-34.,Isobe M, et al. (1992) Localization of the gene encoding the alpha subunit of human interleukin-5 receptor (IL5RA) to chromosome region 3p24-3p26. Genomics. 14(3): 755-8.,Isobe M, et al. (1992) Localization of the gene encoding the alpha subunit of human interleukin-5 receptor (IL5RA) to chromosome region 3p24-3p26. Genomics. 14(3): 755-8.
URL https://www.targetmol.com/recombinant-protein/il5ra_protein_human_recombinant_his_tag_

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