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サプライヤー
TargteMol
カタログNo.
TMPY-01834
製品名称
CD16/FCGR3 Protein, Mouse, Recombinant (aa 32-215, His)
タンパク質名
CD16/FCGR3
Species
Mouse
HOST
HEK293 Cells
100μg: -
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Overview

Synonyms CD16, Fc receptor, IgG, low affinity III
Characteristics 1.Measured by its ability to bind Human IgG1 , Biotinylated?in a functional ELISA.
2.Loaded Monoclonal Anti-Human CD3 Antibody, Mouse IgG2a on ProA Biosensor, can bind Recombinant Mouse CD16/FCGR3 Protein, His Tag with an affinity constant of 322nM as determined in BLI assay(QC tested).
Endotoxin Level < 1.0 EU/μg of the protein as determined by the LAL method.
Purity 99.40%
Description CD16/FCGR3 Protein, Mouse, Recombinant (aa 32-215, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.6 kDa and the accession number is P08508-1.
Reference Edberg JC, et al. (2002) Genetic linkage and association of Fcgamma receptor IIIA (CD16A) on chromosome 1q23 with human systemic lupus erythematosus. Arthritis Rheum. 46(8): 2132-40.,Li P, et al. (2002) Recombinant CD16A-Ig forms a homodimer and cross-blocks the ligand binding functions of neutrophil and monocyte Fcgamma receptors. Mol Immunol. 38(7): 527-38.,Li P, et al. (2007) Affinity and kinetic analysis of Fcgamma receptor IIIa (CD16a) binding to IgG ligands. J Biol Chem. 282(9): 6210-21.
URL https://www.targetmol.com/recombinant-protein/cd16_fcgr3_protein_mouse_recombinant_ecd_his_tag_hplc_verified

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