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- サプライヤー
- TargteMol
- カタログNo.
- TMPY-01813
- 製品名称
- ACRV1 Protein, Human, Recombinant (His)
- タンパク質名
- ACRV1
- Species
- Human
- HOST
- HEK293 Cells
- 100μg: -
- お問い合わせ
Overview
| Synonyms | SP-10, SPACA2, D11S4365, acrosomal vesicle protein 1 |
|---|---|
| Characteristics | Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Endotoxin Level | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Purity | 94.60% |
| Description | Acrosomal protein SP-1, also known as Acrosomal vesicle protein 1 and ACRV1, is a testis-specific, differentiation antigen, that arises within the acrosomal vesicle during spermatogenesis, and is associated with the acrosomal membranes and matrix of mature sperm. Regulation of cell type-specific gene transcription is central to cellular differentiation and development. During spermatogenesis, a number of testis-specific genes are expressed in a precise spatiotemporal order. The longest transcript of ACRV1 / SP-1 is the most abundant, comprising 53-72% of the total acrosomal vesicle protein 1 messages; the second largest transcript comprises 15-32%; the third and the fourth largest transcripts account for 3.4-8.3% and 8.7-12.5%, respectively; and the remaining transcripts combined account for < 1% of the total acrosomal vesicle protein 1 message. ACRV1 / SP-1 is a testis-specific acrosomal protein that has been detected in several species including humans. It may be involved in sperm-zona binding or penetration, and it is a potential contraceptive vaccine immunogen for humans. ACRV1 / SP-1 may be involved in sperm-zona binding or penetration. It is also a intra-acrosomal protein that is considered to be a vaccine candidate for immunocontraception. |
| Reference | Abhyankar,M.M. et al., 2007, J Biol Chem. 282?(50): 36143-54.,Kurth,B.E. et al., 1993, Anat Rec. 236?(4):619-25.,Golden WL, et al.,1994, Genomics.18?(2): 446-9.,Foster,J.A. et al., 1994, Biol Reprod. 51?(6):1222-31.,Wright RM, et al.,1990, Biol Reprod. 42?(4): 693-701. |
| URL | https://www.targetmol.com/recombinant-protein/acrv1_protein_human_recombinant_his_tag_ |
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