タンパク質、抗体、アッセイキット
タンパク質カタログ
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- サプライヤー
- TargteMol
- カタログNo.
- TMPY-01806
- 製品名称
- CD9 Protein, Human, Recombinant (His)
- タンパク質名
- CD9
- Species
- Human
- HOST
- HEK293 Cells
- 50μg: -
- お問い合わせ
Overview
Synonyms | BTCC-1, DRAP-27, TSPAN29, MRP-1, CD9 molecule, MIC3, TSPAN-29 |
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Characteristics | Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
Endotoxin Level | < 1.0 EU/μg of the protein as determined by the LAL method. |
Purity | 98.20% |
Description | The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD9 is a member of the transmembrane 4 superfamily, which is also known as the tetraspanin family. CD9 is a cell surface glycoprotein with 4 hydrophobic domains that are described as complex with integrins and other transmembrane 4 superfamily members. It is found expressed on the surface of the exosomes. The protein takes part in cellular signal transduction events and thus play a role in the regulation of cell development and activation, growth and motility. Besides, CD9 seems to be a key role in the egg-sperm fusion during the mammalian fertilization processes. CD9 is found on the membrane of the oocytes and also appears to intervene in maintaining the normal shape of oocyte microvilli. |
Reference | Ho IC,et al.(2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.,Franois Le Naour,et al.(2000) Severely Reduced Female Fertility in CD9-Deficient Mice. Science. 287(5451): 319-21.,Zola H,et al.(2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.,Matesanz-Isabel J,et al.(2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12 |
URL | https://www.targetmol.com/recombinant-protein/cd9_protein_human_recombinant_his_tag_ |