EphB4 Protein, Mouse, Recombinant (hFc) [TMPY-01786]

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Synonyms	MDK2, Htk, Myk1, AI042935, Tyro11, EPH receptor B4
Characteristics	Measured by its binding ability in a functional ELISA. Immobilized Mouse Ephrin B2 His at 2 μg/ml (100 μl/well) can bind Mouse EphB4 hFc , the EC50 of Mouse EphB4 hFc is 2.0-10.0 ng/mL.
Endotoxin Level	< 1.0 EU/μg of the protein as determined by the LAL method.
Purity	97.30%
Description	EphB4 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 84.7 kDa and the accession number is P54761-1.
Reference	Davalos V, et al. (2006) EPHB4 and survival of colorectal cancer patients. Cancer Res. 66(18): 8943-8.,Kertesz N, et al. (2006) The soluble extracellular domain of EphB4 (sEphB4) antagonizes EphB4-EphrinB2 interaction, modulates angiogenesis, and inhibits tumor growth. Blood. 107(6): 2330-8.,Zhao C, et al. (2006) Bidirectional ephrinB2-EphB4 signaling controls bone homeostasis. Cell Metab. 4(2): 111-21.,Taylor AC, et al. (2007) EphB4 expression along adult rat microvascular networks: EphB4 is more than a venous specific marker. Microcirculation. 14(3): 253-67.,Noren NK, et al. (2007) Paradoxes of the EphB4 receptor in cancer. Cancer Res. 67(9): 3994-7.
URL	https://www.targetmol.com/recombinant-protein/ephb4_protein_mouse_recombinant_hfc_tag_

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