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タンパク質、抗体、アッセイキット

タンパク質カタログ

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サプライヤー
TargteMol
カタログNo.
TMPY-01750
製品名称
HVEM Protein, Human, Recombinant (His)
タンパク質名
HVEM
Species
Human
HOST
HEK293 Cells
100μg: -
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Overview

Synonyms CD270, HVEA, TR2, HVEM, ATAR, tumor necrosis factor receptor superfamily, member 14, LIGHTR
Characteristics Immobilized Recombinant Human HVEM / TNFRSF14 Protein (His Tag) at 2μg/mL (100μL/well) can bind Recombinant Human BTLA Protein (Fc Tag) , the EC50 is 50-150 ng/mL.
Endotoxin Level < 1.0 EU/μg of the protein as determined by the LAL method.
Purity 98.70%
Description HVEM Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19 kDa and the accession number is A0A024R052.
Reference Heo SK,et al.(2007) HVEM signaling in monocytes is mediated by intracellular calcium mobilization. J Immunol. 179(9): 6305-10.,Pasero C,et al.(2009) A role for HVEM, but not lymphotoxin-beta receptor, in LIGHT-induced tumor cell death and chemokine production. Eur J Immunol. 39(9): 2502-14.,Steinberg MW,et al.(2008) A crucial role for HVEM and BTLA in preventing intestinal inflammation. J Exp Med. 205(6): 1463-76.,Murphy KM,et al.(2006) Balancing co-stimulation and inhibition with BTLA and HVEM. Nat Rev Immunol. 6(9): 671-81.,Cheung TC. Modulation of T cell proliferation through the LIGHT-HVEM-BTLA cosignaling pathway. Recent Pat DNA Gene Seq. 3(3): 177-82.
URL https://www.targetmol.com/recombinant-protein/hvem_protein_human_recombinant_ecd_his_tag_hplc_verified

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