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- サプライヤー
- TargteMol
- カタログNo.
- TMPY-01650
- 製品名称
- CD131 Protein, Human, Recombinant (His)
- タンパク質名
- CD131
- Species
- Human
- HOST
- HEK293 Cells
- 100μg: -
- お問い合わせ
Overview
| Synonyms | CDw131, IL5RB, colony stimulating factor 2 receptor, β, low-affinity (granulocyte-macrophage), CD131, IL3RB, colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage), SMDP5 |
|---|---|
| Characteristics | Measured by its binding ability in a functional ELISA. Immobilized human CD131 at 10 μg/ml (100 μl/well) can bind human Fc-GMCSF, The EC50 of human Fc-GMCSF is 250-500 ng/ml. |
| Endotoxin Level | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Purity | 97.80% |
| Description | CD131 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50 kDa and the accession number is P32927-1. |
| Reference | Selleri S,et al.(2008) GM-CSF/IL-3/IL-5 receptor common beta chain (CD131) expression as a biomarker of antigen-stimulated CD8+ T cells. J Transl Med. 6:17.,Dirksen U,et al.(1997) Human pulmonary alveolar proteinosis associated with a defect in GM-CSF/IL-3/IL-5 receptor common beta chain expression. J Clin Invest. 100(9): 2211-7.,Woodcock,et al.(1994) Three residues in the common beta chain of the human GM-CSF, IL-3 and IL-5 receptors are essential for GM-CSF and IL-5 but not IL-3 high affinity binding and interact with Glu21 of GM-CSF. EMBO J. 13(21): 5176-85. |
| URL | https://www.targetmol.com/recombinant-protein/cd131_protein_human_recombinant_his_tag_ |
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