CEACAM5 Protein, Human, Recombinant (His) [TMPY-01647]

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Synonyms	CD66e, CEA, carcinoembryonic antigen-related cell adhesion molecule 5
Characteristics	1. Immobilized Anti-CEA Antibody at 2 μg/mL (100 μL/well) can bind Recombinant Human CEACAM5/CD66e Protein (His Tag), the EC50 is 5.5-16 ng/mL.<br> 2. Loaded Anti-Human CEACAM5 antibody, human IgG1 on ProA?Biosensor, can bind Recombinant Human CEACAM5 Protein, His Tag with an affinity constant of 3.72 nM as determined in a BLI assay (Routinely tested).
Endotoxin Level	< 1.0 EU/μg of the protein as determined by the LAL method.
Purity	SDS-PAGE: 98.2%; SEC-HPLC: 98.2%
Description	CEACAM5 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 72.8 kDa and the accession number is A0A024R0K5.
Reference	Liebig B, et al. (2005) Forced expression of deltaN-TCF-1B in colon cancer derived cell lines is accompanied by the induction of CEACAM5/6 and mesothelin. Cancer Lett. 223(1): 159-67.,Blumenthal RD, et al. (2005) Inhibition of adhesion, invasion, and metastasis by antibodies targeting CEACAM6 (NCA-90) and CEACAM5 (Carcinoembryonic Antigen). Cancer Res. 65(19): 8809-17.,Baczyska D, et al. (2003) The tumorigenic potential of human CX-1 colon adenocarcinoma cells depends on carcinoembryonic antigen (CEACAM5) expression. Cell Mol Biol Lett. 8(2): 471-86.
URL	https://www.targetmol.com/recombinant-protein/ceacam5_protein_human_recombinant_his_tag_hplc_verified

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