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- サプライヤー
- TargteMol
- カタログNo.
- TMPY-01604
- 製品名称
- CTLA-4 Protein, Mouse, Recombinant (His)
- タンパク質名
- CTLA-4
- Species
- Mouse
- HOST
- HEK293 Cells
- 100μg: -
- お問い合わせ
Overview
| Synonyms | cytotoxic T-lymphocyte-associated protein 4, Ctla-4, Ly-56, Cd152 |
|---|---|
| Characteristics | 1. Immobilized Recombinant Mouse CD80 / B7-1 Protein (Fc Tag) at 2μg/mL (100μL/well) can bind Recombinant Mouse CTLA4 / CD152 Protein (ECD,His Tag) , the EC50 is 1.0-3.0 ng/mL. 2. Measured by its ability to inhibit IL-2 secretion by stimulated Jurkat human acute T cell leukemia cells. The ED50 for this effect is 0.1-0.5μg/mL when stimulated with 1 μg/mL Recombinant Human B7-1/CD80. |
| Endotoxin Level | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Purity | 99.30% |
| Description | CTLA-4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.46 kDa and the accession number is Q6GTR6. |
| Reference | Chin LT,et al.(2008) Immune intervention with monoclonal antibodies targeting CD152 (CTLA-4) for autoimmune and malignant diseases. Chang Gung Med J. 31(1): 1-15.,Holmberg D,et al.(2005) CTLA-4 (CD152) and its involvement in autoimmune disease. Autoimmunity. 38(3): 225-33.,Slavik JM,et al.(1999) CD28/CTLA-4 and CD80/CD86 families: signaling and function. Immunol Res. 19(1): 1-24. |
| URL | https://www.targetmol.com/recombinant-protein/ctla_4_protein_mouse_recombinant_ecd_his_tag_hplc_verified |
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