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タンパク質、抗体、アッセイキット

タンパク質カタログ

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サプライヤー
TargteMol
カタログNo.
TMPY-01460
製品名称
ABHD4 Protein, Human, Recombinant (His)
タンパク質名
ABHD4
Species
Human
HOST
Baculovirus Insect Cells
20μg: -
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Overview

Synonyms abhydrolase domain containing 4, ABH4
Characteristics Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Endotoxin Level < 1.0 EU/μg of the protein as determined by the LAL method.
Purity 90.10%
Description Abhydrolase domain containing 4 (ABHD4), also known as alpha/beta-hydrolase 4 (ABH4) , or lyso-N-acylphosphatidylethanolamine lipase, which belongs to the ABHD4/ABHD5 subfamily of peptidase S33 family. Abhydrolase domain containing (ABHD) gene was a small group belongs to alpha/beta hydrolase superfamily. Known members of this group are all found to be involved in important biochemical processes and related to various diseases. The alpha/beta-hydrolase 4 (ABH4) is a lysophospholipase/phospholipase B that selectively hydrolyzes N-acyl phosphatidylethanolamines (NAPEs) and lysoNAPEs. ABH4 accepts lysoNAPEs bearing both saturated and polyunsaturated N-acyl chains as substrates and displays a distribution that closely mirrors lysoNAPE-lipase activity in mouse tissues. The existence of an NAPE-PLD-independent route for NAE biosynthesis and suggest that ABH4 plays a role in this metabolic pathway by acting as a (lyso)NAPE-selective lipase.
Reference Li F,et al.(2009) An unannotated alpha/beta hydrolase superfamily member, ABHD6 differentially expressed among cancer cell lines. Mol Biol Rep. 36(4): 691-6.,Simon G.M,et al.(2006) Endocannabinoid biosynthesis proceeding through glycerophospho-N-acyl ethanolamine and a role for alpha/beta hydrolase 4 in this pathway. J. Biol. Chem. 281: 26465-72.
URL https://www.targetmol.com/recombinant-protein/abhd4_protein_human_recombinant_his_tag_

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