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- サプライヤー
- TargteMol
- カタログNo.
- TMPY-01459
- 製品名称
- TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (His)
- タンパク質名
- TNFR1/CD120a/TNFRSF1A
- Species
- Human
- HOST
- HEK293 Cells
- 100μg: -
- お問い合わせ
Overview
| Synonyms | p60, TNFR60, CD120a, TNFR1-d2, TNFAR, TBP1, TNFR1, TNF-R-I, FPF, TNF-R, tumor necrosis factor receptor superfamily member 1A, MS5, p55, TNF-R55, TNFR55, p55-R |
|---|---|
| Characteristics | 1. Immobilized human TNFRI-His at 10 μg/mL (100 μl/well) can bind biotinylated human TNFα. The EC50 of biotinylated human TNFα is 5-12 μg/mL. 2. Measured by its ability to inhibit TNFα-mediated cytotoxicity in the L929 mouse fibrosarcoma cells in the presence of metabolic inhibitor actinomycin D. The ED50 for this effect is typically 0.05-0.4μg/mL in the presence of 0.25 ng/mL recombinant human TNFα. |
| Endotoxin Level | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Purity | SDS-PAGE: 96.2%; SEC-HPLC: 87.4% |
| Description | TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.7 kDa and the accession number is P19438-1. |
| Reference | Matesanz-Isabel J,et al.(2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.,Ho IC,et al.(2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.,Cottin V,et al.(2002) Restricted localization of the TNF receptor CD120a to lipid rafts: a novel role for the death domain. The journal of immunology. 168: 4095-102.,Zola H,et al.(2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5. |
| URL | https://www.targetmol.com/recombinant-protein/tnfr1_cd120a_protein_human_recombinant_his_tag_hplc_verified |
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