FGF-18 Protein, Mouse, Recombinant (His) [TMPY-01415]

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Synonyms	D130055P09Rik, FGF-18, fibroblast growth factor 18
Characteristics	1. Measured by its binding ability in a functional ELISA. 2. Immobilized mouse FGF18 at 10 μg/mL (100 μl/well) can bind? Rat FGFR4 , The EC50 of Rat FGFR4 is 0.44 μg/mL.
Endotoxin Level	< 1.0 EU/μg of the protein as determined by the LAL method.
Purity	> 95 % as determined by SDS-PAGE
Description	FGF-18 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.5 kDa and the accession number is A0A7U3JW51.
Reference	Davidson D,et al.(2005) Fibroblast growth factor (FGF) 18 signals through FGF receptor 3 to promote chondrogenesis. J Biol Chem. 280(21): 20509-15.,Ohbayashi N,et al.(2002) FGF18 is required for normal cell proliferation and differentiation during osteogenesis and chondrogenesis. Genes Dev. 16(7): 870-9.,Liu Z,et al.(2007) FGF18 is required for early chondrocyte proliferation, hypertrophy and vascular invasion of the growth plate. Dev Biol. 302(1): 80-91.
URL	https://www.targetmol.com/recombinant-protein/fgf18_protein_mouse_recombinant_his_tag_

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