HER3/ERBB3 Protein, Human, Recombinant (His) [TMPY-01389]

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Synonyms	c-erbB3, LCCS2, p85-sErbB3, p180-ErbB3, HER3, erb-b2 receptor tyrosine kinase 3, c-erbB-3, MDA-BF-1, EEBB3, erbB3-S, p45-sErbB3, ErbB-3
Characteristics	1. Measured by its binding ability in a functional ELISA. 2. Immobilized human ErbB3 at 2 μg/mL (100 μl/well) can bind human NRG1 (isoform Beta1), The EC50 of human NRG1 (isoform Beta1) is 0.43 μg/mL.
Endotoxin Level	< 1.0 EU/μg of the protein as determined by the LAL method.
Purity	SDS-PAGE: 98.5%; SEC-HPLC: 97.6%
Description	HER3/ERBB3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 70.2 kDa and the accession number is P21860-1.
Reference	Plowman G.D.,et al., (1990), Molecular cloning and expression of an additional epidermal growth factor receptor-related gene.Proc. Natl. Acad. Sci. U.S.A. 87:4905-4909.,Kraus M.H.,et al.,(1989), Isolation and characterization of ERBB3, a third member of the ERBB/epidermal growth factor receptor family: evidence for overexpression in a subset of human mammary tumors. Proc. Natl. Acad. Sci. U.S.A. 86:9193-9197.,Katoh M.,et al.,(1993), c-erbB3 gene encodes secreted as well as transmembrane receptor tyrosine kinase.Biochem. Biophys. Res. Commun. 192:1189-1197.
URL	https://www.targetmol.com/recombinant-protein/her3_erbb3_protein_human_recombinant_ecd_his_tag_

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