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- サプライヤー
- TargteMol
- カタログNo.
- TMPY-01386
- 製品名称
- CD155/PVR Protein, Human, Recombinant (His)
- タンパク質名
- CD155/PVR
- Species
- Human
- HOST
- HEK293 Cells
- 100μg: -
- お問い合わせ
Overview
| Synonyms | NECL5, TAGE4, PVS, CD155, HVED, Necl-5, poliovirus receptor |
|---|---|
| Characteristics | 1.Measured by its binding ability in a functional ELISA. Immobilized human CD155 at 2 μg/mL (100 μL/well) can bind human DNAM1 , the EC50 of human DNAM1/CD226 is 50-300 ng/mL. 2.Loaded Human CD226 Protein, hFc Tag on ProA Biosensor, can bind human CD155 protein, His Tag with an affinity constant of 0.87?M as determined in BLI assay (Routinely tested). 3.Loaded Recombinant Human TIGIT Protein, hFc Tag on ProA Biosensor, can bind Recombinant Human CD155/PVR Protein, His Tag with an affinity constant of 0.18 uM as determined in BLI assay (Routinely tested). |
| Endotoxin Level | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Purity | SDS-PAGE: 97.5%; SEC-HPLC: 100% |
| Description | CD155/PVR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.5 kDa and the accession number is P15151-1. |
| Reference | Sato T, et al. (2005) Common signaling pathway is used by the trans-interaction of Necl-5/Tage4/PVR/CD155 and nectin, and of nectin and nectin during the formation of cell-cell adhesion. Cancer Sci. 96(9): 578-89.,Sato T, et al. (2004) Involvement of heterophilic trans-interaction of Necl-5/Tage4/PVR/CD155 with nectin-3 in formation of nectin- and cadherin-based adherens junctions. Genes Cells. 9(9): 791-9.,Minami Y, et al. (2007) Involvement of up-regulated Necl-5/Tage4/PVR/CD155 in the loss of contact inhibition in transformed NIH3T3 cells. Biochem Biophys Res Commun. 352(4): 856-60.,Freistadt MS, et al. (2000) Hematopoietic cells from CD155-transgenic mice express CD155 and support poliovirus replication ex vivo. Microb Pathog. 29(4): 203-12.,Kakunaga S, et al. (2004) Enhancement of serum- and platelet-derived growth factor-induced cell proliferation by Necl-5/Tage4/poliovirus receptor/CD155 through the Ras-Raf-MEK-ERK signaling. J Biol Chem. 279(35): 36419-25. |
| URL | https://www.targetmol.com/recombinant-protein/cd155_pvr_protein_human_recombinant_ecd_his_tag_hplc_verified |
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