DLL1 Protein, Human, Recombinant (His) [TMPY-01379]

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Synonyms	δ1, Delta, delta-like 1 (Drosophila), DL1, δ, δ-like 1 (Drosophila), DELTA1
Characteristics	1. Measured by its ability to bind human NOTCH1 in a functional ELISA. 2. Measured by the ability of the immobilized protein to enhance BMP2-induced alkaline phosphatase activity in C3H10T1/2 mouse embryonic fibroblast cells. The ED50 for this effect is typically 2-20 μg/mL.
Endotoxin Level	< 1.0 EU/μg of the protein as determined by the LAL method.
Purity	SDS-PAGE: 93.1%; SEC-HPLC: 98.1%
Description	DLL1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.4 kDa and the accession number is A0A384P5C6.
Reference	Sun D, et al. (2008) The role of Delta-like 1 shedding in muscle cell self-renewal and differentiation. J Cell Sci. 121(Pt 22): 3815-23.,Dyczynska E, et al. (2007) Proteolytic processing of delta-like 1 by ADAM proteases. J Biol Chem. 282(1): 436-44.,Srensen I, et al. (2009) DLL1-mediated Notch activation regulates endothelial identity in mouse fetal arteries. Blood. 113(22): 5680-8.
URL	https://www.targetmol.com/recombinant-protein/dll1_protein_human_recombinant_his_tag_hplc_verified

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