ICAM-1/CD54 Protein, Mouse, Recombinant (His) [TMPY-01349]

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Synonyms	MALA-2, Ly-47, CD54, intercellular adhesion molecule 1, Icam-1
Characteristics	Measured by the ability of the immobilized protein to support the adhesion of PMA-stimulated HSB2 human peripheral blood acute lymphoblastic leukemia cells. When cells are added to mouse ICAM1 coated plates (12.5 μg/mL, 100 μL/well), approximately > 40% cells will adhere specifically.
Endotoxin Level	< 1.0 EU/μg of the protein as determined by the LAL method.
Purity	97.90%
Description	ICAM-1/CD54 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 51.7 kDa and the accession number is P13597-1.
Reference	Mendez MP,et al.(2006) Shedding of soluble ICAM-1 into the alveolar space in murine models of acute lung injury. Am J Physiol Lung Cell Mol Physiol. 290(5): L962-70.,Lawson C,et al.(2009) ICAM-1 signaling in endothelial cells. Pharmacol Rep. 61(1): 22-32.,Xu H,et al.(2001) The role of ICAM-1 molecule in the migration of Langerhans cells in the skin and regional lymph node. Eur J Immunol. 31(10): 3085-93.,Terol MJ,et al.(2003) Soluble intercellular adhesion molecule-1 (s-ICAM-1/s-CD54) in diffuse large B-cell lymphoma: association with clinical characteristics and outcome. Ann Oncol. 14(3): 467-74.
URL	https://www.targetmol.com/recombinant-protein/icam_1_protein_mouse_recombinant_his_tag_hplc_verified

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