EpCAM/TROP1 Protein, Human, Recombinant (His) [TMPY-01300]

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Synonyms	TROP-1, ESA, EGP40, HNPCC8, EGP314, M4S1, epithelial cell adhesion molecule, MK-1, MIC18, DIAR5, EGP-2, KS1/4, TACSTD1, TROP1, KSA
Characteristics	Measured by the ability of the immobilized protein to support the adhesion of NIH-3T3 mouse embryonic fibroblast cells. When cells are added to EpCAM-His coated plates (1.25μg/mL, 100μL/well), approximately >40% will adhere specifically after 30 minutes at 37℃.
Endotoxin Level	< 1.0 EU/μg of the protein as determined by the LAL method.
Purity	SDS-PAGE: 94%; SEC-HPLC: 90.6%
Description	EpCAM/TROP1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.84 kDa and the accession number is P16422.
Reference	Trzpis M, et al. (2008) EpCAM in morphogenesis. Front Biosci. 13: 5050-5.,Munz M, et al. (2009) The emerging role of EpCAM in cancer and stem cell signaling. Cancer Res. 69(14): 5627-9.,Brunner A, et al. (2008) EpCAM is predominantly expressed in high grade and advanced stage urothelial carcinoma of the bladder. J Clin Pathol. 61(3):307-10.,Carpenter G, et al. (2009) EpCAM: another surface-to-nucleus missile. Cancer Cell. 15(3): 165-6.
URL	https://www.targetmol.com/recombinant-protein/epcam_protein_human_recombinant_ecd_his_tag_hplc_verified

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