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- サプライヤー
- TargteMol
- カタログNo.
- TMPY-01281
- 製品名称
- ACVR2B Protein, Mouse, Recombinant (His)
- タンパク質名
- ACVR2B
- Species
- Mouse
- HOST
- HEK293 Cells
- 100μg: -
- お問い合わせ
Overview
| Synonyms | ActRIIB, activin A receptor, type IIB, 4930516B21Rik |
|---|---|
| Characteristics | 1. Measured by its binding ability in a functional ELISA. Immobilized Mouse ACVR2B at 2μg/mL (100 μl/well) can bind biotinylated mouse INHBA-His , The EC50 of biotinylated mouse INHBA-His is 40-95 ng/mL. 2. Measured by its ability to neutralize Activin-mediated inhibition on MPC11 cell proliferation. The ED50 for this effect is typically 0.2-0.8 ?g/mL in the presence of 10 ng/mL recombinant Activin A. |
| Endotoxin Level | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Purity | 98.40% |
| Description | ACVR2B Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.8 kDa and the accession number is P27040-1. |
| Reference | Kosaki R,et al.(1999) Left-right axis malformations associated with mutations in ACVR2B, the gene for human activin receptor type IIB. Am J Med Genet. 82(1):70-6.,Albertson RC,et al.(2005) Zebrafish acvr2a and acvr2b exhibit distinct roles in craniofacial development. Developmental dynamics 233(4): 1405-18.,Dupont S,et al.(2001) No evidence for linkage or for diabetes-associated mutations in the activin type 2B receptor gene (ACVR2B) in French patients with mature-onset diabetes of the young or type 2 diabetes. Diabetes 50(5):1219-21.,Walsh S,et al.(2007) Activin-type II receptor B (ACVR2B) and follistatin haplotype associations with muscle mass and strength in humans. J Appl Physiol. 102(6):2142-8. |
| URL | https://www.targetmol.com/recombinant-protein/acvr2b_protein_mouse_recombinant_his_tag_ |
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