TROP-2 Protein, Human, Recombinant (His) [TMPY-01262]

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Synonyms	TROP2, M1S1, GA733-1, TROP-2, GA7331, tumor-associated calcium signal transducer 2, GP50, EGP-1, EGP1, TACD2
Characteristics	1. Immobilized Anti-TROP2 Antibody at 2μg/mL (100 μL/well) can bind Recombinant Human TROP2/TACSTD2 Protein (His Tag) , the EC50 is 1.6-4.8 ng/mL. 2. Loaded Anti-Human TROP2 antibody, human IgG1 on ProA Biosensor, can bind Recombinant Human TROP2 Protein, His Tag with an affinity constant of 1.64 nM as determined in BLI assay (Routinely tested).
Endotoxin Level	< 1.0 EU/μg of the protein as determined by the LAL method.
Purity	SDS-PAGE: 94.3%; SEC-HPLC: 91.9%
Description	TROP-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 29.4 kDa and the accession number is P09758.
Reference	Ripani E,et al.(1998) Human Trop-2 is a tumor-associated calcium signal transducer. Int J Cancer. 76(5): 671-6.,Wang J,et al.(2008) Identification of Trop-2 as an oncogene and an attractive therapeutic target in colon cancers. Mol Cancer Ther. 7(2): 280-5.
URL	https://www.targetmol.com/recombinant-protein/trop2_protein_human_recombinant_ecd_his_tag_hplc_verified

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