IL-7R alpha/CD127 Protein, Human, Recombinant (His) [TMPY-01209]

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Synonyms	IL7RA, ILRA, CD127, CDW127, IL-7R-α, IL-7R-alpha, IL-7R, IL7R α/CD127, interleukin 7 receptor
Characteristics	Measured by its ability to bind biotinylated mouse TSLP-his in functional ELISA.
Endotoxin Level	< 1.0 EU/μg of the protein as determined by the LAL method.
Purity	SDS-PAGE: 96%; SEC-HPLC: 95.4%
Description	IL-7R alpha/CD127 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.3 kDa and the accession number is P16871-1.
Reference	Crawley AM,et al.(2010) Soluble IL-7R alpha (sCD127) inhibits IL-7 activity and is increased in HIV infection. J Immunol. 184(9): 4679-87.,Kiazyk SA,et al.(2008) Loss of CD127 expression links immune activation and CD4(+) T cell loss in HIV infection. Trends Microbiol. 16(12): 567-73.,Akkad DA,et al.(2009) Variation in the IL7RA and IL2RA genes in German multiple sclerosis patients. J Autoimmun. 32(2): 110-5.,Vranjkovic A,et al.(2007) IL-7 decreases IL-7 receptor alpha (CD127) expression and induces the shedding of CD127 by human CD8+ T cells. Int Immunol. 19(12): 1329-39.
URL	https://www.targetmol.com/recombinant-protein/il7r_alpha_cd127_protein_human_recombinant_ecd_his_tag_hplc_verified

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