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- サプライヤー
- TargteMol
- カタログNo.
- TMPY-01205
- 製品名称
- CD64 Protein, Mouse, Recombinant (His)
- タンパク質名
- CD64
- Species
- Mouse
- HOST
- HEK293 Cells
- 100μg: -
- お問い合わせ
Overview
| Synonyms | Fc receptor, IgG, high affinity I, IGGHAFC, AI323638, FcgammaRI, CD64, FcγRI, AV092959 |
|---|---|
| Characteristics | 1. Immobilized Rituximab (IgG1) at 1 μg/mL can bind Mouse FcγRI / CD64 recombinant protein, the EC50 is 16-35 ng/mL. 2. Immobilized Anti-CD3 antibody, mouse IgG2a at 2 μg/mL (100 μL/well) can bind Recombinant Mouse CD64 / FCGR1 Protein (His Tag) , the EC50 is 0.8-2.4 ng/mL(QC tested). 3.Loaded Mouse FcγRI / CD64 recombinant protein on His1K Biosensor, can bind Bevacizumab (IgG1) with an affinity constant of 0.12 ?M as determined in a BLI assay. 4.Loaded Mouse FcγRI / CD64 recombinant protein on His1K Biosensor, can bind Nivolumab (IgG4) with an affinity constant of 0.28 ?M as determined in a BLI assay. 5.Captured? Mouse FcγRI / CD64 recombinant protein?on?Anti-His?Chip?can?bind?Bevacizumab (IgG1) with?an?affinity?constant?of?0.12 ?M as determined in an SPR assay. 6.Captured?Mouse FcγRI / CD64 recombinant protein ?on?Anti-His?Chip?can?bind?Nivolumab (IgG4) with?an?affinity?constant?of?0.69??M?as?determined?in?an?SPR?assay?(Biacore?T200). 7. The purity of Mouse CD64 / FCGR1 Protein (His Tag) is more than 95% and the molecular weight of this protein is around 40-50 kDa verified by SEC-MALS. 8.Loaded Monoclonal Anti-Human CD3 Antibody, Mouse IgG2a on ProA Biosensor, can bind Recombinant Mouse CD64 Protein, His Tag with an affinity constant of 3.46nM as determined in BLI assay(QC tested). |
| Endotoxin Level | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Purity | 98.30% |
| Description | CD64 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32 kDa and the accession number is P26151. |
| Reference | Allen J.M., et al.,(1988), Nucleotide sequence of three cDNAs for the human high affinity Fc receptor (FcRI). Nucleic Acids Res. 16:11824-11824.,Allen J.M., et al., (1989), Isolation and expression of functional high-affinity Fc receptor complementary DNAs.Science 243:378-381.,Porges A.J., et al.,(1992), Novel Fc gamma receptor I family gene products in human mononuclear cells.J. Clin. Invest. 90:2102-2109. |
| URL | https://www.targetmol.com/recombinant-protein/cd64_protein_mouse_recombinant_his_tag_hplc_verified |
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