CD40 Protein, Human, Recombinant (His) [TMPY-01181]

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Synonyms	CDW40, CD40 molecule, TNF receptor superfamily member 5, TNFRSF5, p50, Bp50
Characteristics	1. Immobilized Human CD40 His at 2 μg/mL (100 μL/well) can bind Human CD40 Ligand (ECD, hFc & AVI Tag), Biotinylated , the EC50 is 6-20 ng/mL. 2.Loaded Recombinant Human CD40 Protein, His Tag on His1K Biosensor, can bind Recombinant Human CD40 Ligand Protein, hFc Tag with an affinity constant of 5.88 nM as determined in BLI assay (Routinely tested).
Endotoxin Level	< 1.0 EU/μg of the protein as determined by the LAL method.
Purity	SDS-PAGE: 95.8%; SEC-HPLC: 99.1%
Description	CD40 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.7 kDa and the accession number is A0A0S2Z3C7.
Reference	van Kooten C,et al.(2000). CD40-CD40 ligand. J Leukoc Biol. 67 (1): 2-17.,Chatzigeorgiou A,et al.(2009) CD40/CD40L signaling and its implication in health and disease. Biofactors. 35(6): 474-83.,Lievens D,et al.(2009) The multi-functionality of CD40L and its receptor CD40 in atherosclerosis. Thromb Haemost. 102(2): 206-14.,Bhushan A,et al.(2002). CD40:CD40L interactions in X-linked and non-X-linked hyper-IgM syndromes. Immunol Res. 24 (3): 311-24.,Li R,et al.(2009) Expression of CD40 and CD40L in Gastric Cancer Tissue and Its Clinical Significance. Int J Mol Sci. 10(9): 3900-17.
URL	https://www.targetmol.com/recombinant-protein/cd40_protein_human_recombinant_ecd_his_tag_hplc_verified

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