タンパク質、抗体、アッセイキット
タンパク質カタログ
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- サプライヤー
- TargteMol
- カタログNo.
- TMPY-01168
- 製品名称
- ALK-1 Protein, Human, Recombinant (His)
- タンパク質名
- ALK-1
- Species
- Human
- HOST
- HEK293 Cells
- 100μg: -
- お問い合わせ
Overview
Synonyms | ALK1, ALK-1, activin A receptor type II-like 1, HHT2, TSR-I, ACVRLK1, ORW2, HHT, SKR3 |
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Characteristics | Measured by its ability to inhibit BMP9 induced alkaline phosphatase production by MC3T3E1 mouse chondrogenic cells. David, L. et al. (2007) Blood 109:1953. The ED50 for this effect is typically 50-200 ng/mL in the presence of 2 ng/mL of recombinant human BMP9. |
Endotoxin Level | < 1.0 EU/μg of the protein as determined by the LAL method. |
Purity | 98.70% |
Description | ALK-1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 12.3 kDa and the accession number is A0A0S2Z310. |
Reference | French Rendu-Osler network, et al. (2004) Molecular screening of ALK1/ACVRL1 and ENG genes in hereditary hemorrhagic telangiectasia in France. Hum Mutat. 23(4): 289-299.,Argyriou L, et al. (2006) Novel mutations in the ENG and ACVRL1 genes causing hereditary hemorrhagic teleangiectasia. Int J Mol Med. 17(4):655-9.,Simon M, et al. (2006) Association of a polymorphism of the ACVRL1 gene with sporadic arteriovenous malformations of the central nervous system. J Neurosurg. 104(6): 945-9. |
URL | https://www.targetmol.com/recombinant-protein/alk_1_protein_human_recombinant_his_tag_ |