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- サプライヤー
- TargteMol
- カタログNo.
- TMPY-01166
- 製品名称
- TNFR2/CD120b/TNFR1B Protein, Human, Recombinant (His)
- タンパク質名
- TNFR2/CD120b/TNFR1B
- Species
- Human
- HOST
- HEK293 Cells
- 100μg: -
- お問い合わせ
Overview
| Synonyms | TNFR80, p75, TNF-R75, TNFR1B, tumor necrosis factor receptor superfamily, member 1b, TBPII, CD120b, TNFBR, p75TNFR, TNFR2, TNF-R-II |
|---|---|
| Characteristics | 1. Measured by its ability to inhibit TNF-α mediated cytotoxicity in L-929 mouse fibrosarcoma cells in the presence of the metabolic inhibitor actinomycin D. The ED50 for this effect is typically 0.2-2 μg/ml in the presence of 0.25 ng/mL recombinant human TNF-α. 2. Measured by its binding ability in a functional ELISA. Immobilized Human TNF-alpha at 2 μg/ml (100 μl/well) can bind Human TNFR2/TNFRSF1B His, the EC50 of Human TNFR2/TNFRSF1B His is 2.0-12.0 ng/mL. |
| Endotoxin Level | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Purity | SDS-PAGE: 98.3%; SEC-HPLC: 96.6% |
| Description | TNFR2/CD120b/TNFR1B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.6 kDa and the accession number is P20333-1. |
| Reference | Guo G,et al.(1999) Role of TNFR1 and TNFR2 receptors in tubulointerstitial fibrosis of obstructive nephropathy. Am J Physiol. 277(5): 766-72.,Komata T,et al.(1999) Association of tumor necrosis factor receptor 2 (TNFR2) polymorphism with susceptibility to systemic lupus erythematosus. Tissue Antigens. 53(6): 527-33.,Tsuchiya N,et al.(2001) Analysis of the association of HLA-DRB1, TNFalpha promoter and TNFR2 (TNFRSF1B) polymorphisms with SLE using transmission disequilibrium test. Genes Immun. 2(6): 317-22. |
| URL | https://www.targetmol.com/recombinant-protein/tnfr_2_cd120b_protein_human_recombinant_ecd_his_tag_hplc_verified |
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