ICAM-1/CD54 Protein, Human, Recombinant (His) [TMPY-01142]

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Synonyms	P3.58, BB2, ICAM-1, CD54, intercellular adhesion molecule 1
Characteristics	Measured by the ability of the immobilized protein to support the adhesion of PMA-stimulated HSB2 human peripheral blood acute lymphoblastic leukemia cells. When cells are added to ICAM1-coated plates (12.5 μg/ml, 100 μl/well), approximately 30%-60% will adhere specifically.
Endotoxin Level	< 1.0 EU/μg of the protein as determined by the LAL method.
Purity	SDS-PAGE: 95.4%; SEC-HPLC: 97.9%
Description	ICAM-1/CD54 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 51 kDa and the accession number is A0A384MEK5.
Reference	Terol MJ,et al.(2003) Soluble intercellular adhesion molecule-1 (s-ICAM-1/s-CD54) in diffuse large B-cell lymphoma: association with clinical characteristics and outcome. Ann Oncol. 14(3): 467-74.,Mendez MP,et al.(2006) Shedding of soluble ICAM-1 into the alveolar space in murine models of acute lung injury. Am J Physiol Lung Cell Mol Physiol. 290(5): L962-70.,Xu H,et al.(2001) The role of ICAM-1 molecule in the migration of Langerhans cells in the skin and regional lymph node. Eur J Immunol. 31(10): 3085-93.,Lawson C,et al.(2009) ICAM-1 signaling in endothelial cells. Pharmacol Rep. 61(1): 22-32.
URL	https://www.targetmol.com/recombinant-protein/icam_1_protein_human_recombinant_his_tag_hplc_verified

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