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タンパク質カタログ
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- サプライヤー
- TargteMol
- カタログNo.
- TMPY-01107
- 製品名称
- TIMP-1 Protein, Human, Recombinant
- タンパク質名
- TIMP-1
- Species
- Human
- HOST
- HEK293 Cells
- 20μg: -
- お問い合わせ
Overview
| Synonyms | EPO, TIMP metallopeptidase inhibitor 1, TIMP-1, HCI, CLGI, TIMP, EPA |
|---|---|
| Characteristics | Measured by its ability to inhibit human MMP-2 cleavage of a fluorogenic peptide substrate MCA-PLGL-DPA-AR-NH2. The IC50 value is < 6 nM. |
| Endotoxin Level | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Purity | SDS-PAGE: 98.2%; SEC-HPLC: 96.6% |
| Description | TIMP-1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 21 kDa and the accession number is P01033. |
| Reference | Wang X, et al. (1999) Analysis of coding sequences for tissue inhibitor of metalloproteinases 1 (TIMP-1) and 2 (TIMP2) in patients with aneurysms. Matrix Biol. 18(2):121-4.,Hornebeck W (2004). Down-regulation of tissue inhibitor of matrix metalloprotease-1 (TIMP-1) in aged human skin contributes to matrix degradation and impaired cell growth and survival.. Pathol. Biol. 51 (10): 569-73.,Soini Y, et al. (2001) Expression of MMP2, MMP9, MT1-MMP, TIMP-1, and TIMP2 mRNA in valvular lesions of the heart. J Pathol. 194(2):225-31. |
| URL | https://www.targetmol.com/recombinant-protein/timp_1_protein_human_recombinant |
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