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サプライヤー
TargteMol
カタログNo.
TMPY-01103
製品名称
CD25/IL2R alpha Protein, Human, Recombinant (His)
タンパク質名
CD25/IL2R alpha
Species
Human
HOST
HEK293 Cells
100μg: -
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Overview

Synonyms interleukin 2 receptor, α, IL-2RA, IDDM10, IL2R, interleukin 2 receptor, alpha, TCGFR, CD25, p55, CD25/IL2R α
Characteristics Measured by its ability to inhibit IL2-induced proliferation of M07e cells. The ED50 for this effect is 0.2-1.2 μg/mL in the presence of 30 ng/mL of recombinant human IL2.
Endotoxin Level < 1.0 EU/μg of the protein as determined by the LAL method.
Purity 99%
Description CD25/IL2R alpha Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23.3 kDa and the accession number is P01589.
Reference Chistiakov DA, et al. (2008) The crucial role of IL-2/IL-2RA-mediated immune regulation in the pathogenesis of type 1 diabetes, an evidence coming from genetic and animal model studies. Immunol Lett. 118(1): 1-5.,Olejniczak K, et al. (2008) Biological properties of interleukin 2 and its role in pathogenesis of selected diseases--a review. Med Sci Monit. 14(10): RA179-89.,Bien E, et al. (2008) Serum soluble interleukin 2 receptor alpha in human cancer of adults and children: a review. Biomarkers. 13(1): 1-26.,Driesen J, et al. (2008) CD25 as an immune regulatory molecule expressed on myeloid dendritic cells. Immunobiology. 213(9-10): 849-58.
URL https://www.targetmol.com/recombinant-protein/cd25_il2r_alpha_protein_human_recombinant_ecd_his_tag_hplc_verified

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