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- サプライヤー
- TargteMol
- カタログNo.
- TMPY-01076
- 製品名称
- gp130/IL6ST Protein, Human, Recombinant (His & hFc)
- タンパク質名
- gp130/IL6ST
- Species
- Human
- HOST
- HEK293 Cells
- 20μg: -
- お問い合わせ
Overview
| Synonyms | interleukin 6 signal transducer, IL-6RB, CD130, CDW130, GP130 |
|---|---|
| Characteristics | Measured by its ability to inhibit the IL-6Rα enhancement of IL-6 activity on M1 mouse myeloid leukemia cell. The ED50 for this effect is typically 0.2-0.8 μg/mL in the presence of 50 ng/mL recombinant human IL-6sR and 100 ng/mL recombinant human IL-6. |
| Endotoxin Level | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Purity | 97.80% |
| Description | gp130/IL6ST Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 96 kDa and the accession number is P40189-1. |
| Reference | Giordano V, et al. (1997) Shc mediates IL-6 signaling by interacting with gp130 and Jak2 kinase. J Immunol. 158 (9): 4097-103.,Kim H, et al. (1997) Transmembrane domain of gp130 contributes to intracellular signal transduction in hepatic cells. J Biol Chem. 272 (49): 30741-7.,Hibi, et al. (1990) Molecular cloning and expression of an IL-6 signal transducer, gp130. Cell. 63 (6): 1149-57. |
| URL | https://www.targetmol.com/recombinant-protein/gp130_il6st_protein_human_recombinant_his_hfc_tag_ |
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