検索タンパク質、抗体、アッセイキット
タンパク質カタログ
輸入に関する法規制チェックは、御見積のご依頼をいただいた際に行います。
法規制によっては、定価として記載の価格に追加の費用が発生する場合や供給出来ない場合がございますので、あらかじめご了承ください。
- サプライヤー
- TargteMol
- カタログNo.
- TMPY-01075
- 製品名称
- Von Willebrand Factor/vWF Protein, Human, Recombinant (His)
- タンパク質名
- Von Willebrand Factor/vWF
- Species
- Human
- HOST
- CHO Cells
- 100μg: -
- お問い合わせ
Overview
| Synonyms | von Willebrand factor, VWD, F8VWF |
|---|---|
| Characteristics | Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Endotoxin Level | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Purity | 87.20% |
| Description | Von Willebrand Factor (VWF) is a multimeric glycoprotein involved in hemostasis in blood, binds receptors on the surface of platelets and in connective tissue, thereby mediating the adhesion of platelets to sites of vascular injury. From studies it appears that VWF protein uncoils under these circumstances, decelerating passing platelets. VWF protein is deficient or defective in von Willebrand disease (VWD) and is involved in a large number of other diseases, including thrombosis, thrombotic thrombocytopenic purpura, Stroke, Heyde's syndrome, possibly hemolytic-uremic syndrome and so on. |
| Reference | Batlle J,et al.(2009) Von Willebrand factor/factor VIII concentrates in the treatment of von Willebrand disease. Blood Coagul Fibrinolysis. 20(2):89-100.,Auton M,et al.(2010) The mechanism of VWF-mediated platelet GPIbalpha binding. Biophys J. 99(4):1192-201.,Sadler JE. (1998) Biochemistry and genetics of von Willebrand factor. Annu Rev Biochem, 67: 395-424.,Sadler JE. (2009) von Willebrand factor assembly and secretion. J Thromb Haemost. 7 Suppl 1:24-7.,Lpez JA,et al.(2010) VWF self-association: more bands for the buck. Blood. 116(19):3693-4.,Bowen DJ. (2010) Sugar targets VWF for the chop. Blood. 115(13):2565. |
| URL | https://www.targetmol.com/recombinant-protein/von_willebrand_factor_vwf_protein_human_recombinant_his_tag_hplc_verified |
お問い合わせリスト