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タンパク質、抗体、アッセイキット

タンパク質カタログ

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サプライヤー
TargteMol
カタログNo.
TMPY-01068
製品名称
CD70 Protein, Human, Recombinant (hFc)
タンパク質名
CD70
Species
Human
HOST
HEK293 Cells
100μg: -
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Overview

Synonyms TNFSF7, CD27L, CD27LG, CD70 molecule
Characteristics Measured by its binding ability in a functional ELISA. Immobilized Human CD27 His at 2 μg/ml (100 μl/well) can bind Human CD70 hFc , the EC50 of Human CD70 hFc is 15-60 ng/mL.
Endotoxin Level < 1.0 EU/μg of the protein as determined by the LAL method.
Purity 91.50%
Description CD70 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.5 kDa and the accession number is A0A0U5JA32.
Reference Grewal IS. (2008) CD70 as a therapeutic target in human malignancies. Expert Opin Ther Targets. 12(3): 341-51.Boursalian TE, et al. (2009) Targeting CD70 for human therapeutic use. Adv Exp Med Biol. 647: 108-19.,Keller AM, et al. (2007) Costimulatory ligand CD70 is delivered to the immunological synapse by shared intracellular trafficking with MHC class II molecules. Proc Natl Acad Sci U S A. 104(14): 5989-94.,Adam PJ, et al. (2006) CD70 (TNFSF7) is expressed at high prevalence in renal cell carcinomas and is rapidly internalised on antibody binding. Br J Cancer. 95(3): 298-306.
URL https://www.targetmol.com/recombinant-protein/cd70_protein_human_recombinant_hfc_tag_

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