タンパク質、抗体、アッセイキット
タンパク質カタログ
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- サプライヤー
- TargteMol
- カタログNo.
- TMPY-01068
- 製品名称
- CD70 Protein, Human, Recombinant (hFc)
- タンパク質名
- CD70
- Species
- Human
- HOST
- HEK293 Cells
- 100μg: -
- お問い合わせ
Overview
Synonyms | TNFSF7, CD27L, CD27LG, CD70 molecule |
---|---|
Characteristics | Measured by its binding ability in a functional ELISA. Immobilized Human CD27 His at 2 μg/ml (100 μl/well) can bind Human CD70 hFc , the EC50 of Human CD70 hFc is 15-60 ng/mL. |
Endotoxin Level | < 1.0 EU/μg of the protein as determined by the LAL method. |
Purity | 91.50% |
Description | CD70 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.5 kDa and the accession number is A0A0U5JA32. |
Reference | Grewal IS. (2008) CD70 as a therapeutic target in human malignancies. Expert Opin Ther Targets. 12(3): 341-51.Boursalian TE, et al. (2009) Targeting CD70 for human therapeutic use. Adv Exp Med Biol. 647: 108-19.,Keller AM, et al. (2007) Costimulatory ligand CD70 is delivered to the immunological synapse by shared intracellular trafficking with MHC class II molecules. Proc Natl Acad Sci U S A. 104(14): 5989-94.,Adam PJ, et al. (2006) CD70 (TNFSF7) is expressed at high prevalence in renal cell carcinomas and is rapidly internalised on antibody binding. Br J Cancer. 95(3): 298-306. |
URL | https://www.targetmol.com/recombinant-protein/cd70_protein_human_recombinant_hfc_tag_ |