IL-4R Protein, Human, Recombinant (His) [TMPY-01055]

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Synonyms	interleukin 4 receptor, IL4RA, IL4R, CD124, IL-4RA
Characteristics	1. Measured by its binding ability in a functional ELISA. Immobilized human IL4R-His at 10 μg/mL (100 μl/well) can bind biotinylated human IL4 . The EC50 of biotinylated human IL4 is 20.8-48.5 ng/mL. 2.Measured by its ability to inhibit IL-4-induced proliferation of TF-1 human erythroleukemic cells. The ED50 for this effect is typically 5-25 ng/ml in the presence of 0.2 ng/mL of Recombinant human IL-4.
Endotoxin Level	< 1.0 EU/μg of the protein as determined by the LAL method.
Purity	SDS-PAGE: 99.3%; SEC-HPLC: 99.9%
Description	IL-4R Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.18 kDa and the accession number is P24394-1.
Reference	Matesanz-Isabel J,et al.(2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.,Ho IC,et al.(2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.,Zola H,et al.(2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
URL	https://www.targetmol.com/recombinant-protein/il4r_protein_human_recombinant_ecd_his_tag_hplc_verified

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