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タンパク質、抗体、アッセイキット

タンパク質カタログ

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サプライヤー
TargteMol
カタログNo.
TMPY-01037
製品名称
CSF1R Protein (Met1-Glu512), Human, Recombinant (His)
タンパク質名
CSF1R
Species
Human
HOST
HEK293 Cells
100μg: -
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Overview

Synonyms CSF-1R, FIM2, M-CSF-R, MCSF Receptor, colony stimulating factor 1 receptor, CSFR, CD115, HDLS, FMS, C-FMS
Characteristics 1.Measured by its binding ability in a functional ELISA. Immobilized human CSF1R at 10 μg/mL (100 μl/well) can bind biotinylated human CSF-1 , The EC50 of biotinylated human CSF-1 is 8 ng/mL.
2.Captured M-CSF/CSF1 Protein, Human on proA Chip?can?bind CSF1R with an affinity constant of 0.1468 ?M as determined in a SPR assay (Routinely tested).
Endotoxin Level < 1.0 EU/μg of the protein as determined by the LAL method.
Purity SDS-PAGE: 97.7%; SEC-HPLC: 99.7%
Description CSF1R Protein (Met1-Glu512), Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 56 kDa and the accession number is P07333-1.
Reference Sherr CJ. (1990) The colony-stimulating factor 1 receptor: pleiotropy of signal-response coupling. Lymphokine Res. 9(4): 543-8.,Kacinski BM. (1997) CSF-1 and its receptor in breast carcinomas and neoplasms of the female reproductive tract. Mol Reprod Dev. 46(1): 71-4.,Sapi E,et al.(1999) The role of CSF-1 in normal and neoplastic breast physiology. Proc Soc Exp Biol Med. 220(1): 1-8.,Bonifer C,et al.(2008) The transcriptional regulation of the Colony-Stimulating Factor 1 Receptor (csf1r) gene during hematopoiesis. Front Biosci. 13: 549-60.,Sapi E. (2004) The role of CSF-1 in normal physiology of mammary gland and breast cancer: an update. Exp Biol Med (Maywood). 229(1): 1-11.
URL https://www.targetmol.com/recombinant-protein/csf1r_protein_human_recombinant_ecd_his_tag_hplc_verified

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