CD38 Protein, Human, Recombinant (His) [TMPY-01023]

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Synonyms	CD38 molecule, ADPRC1, ADPRC 1, T10
Characteristics	1. Measured by its ability to convert the substrate nicotinamide guanine dinucleotide(NGD+) to cyclic GDPribose. The specific activity is > 2,500 pmoles/min/μg. 2. Measured by its binding ability in a functional ELISA. Immobilized Human CD38 His at 2 μg/ml (100 μl/well) can bind Mouse Anti-CD38 Antibody , the EC50 of Mouse Anti-CD38 Antibody is 30-120 ng/mL. 3.Captured Daratumumab on anti-human IgG Fc via CM5 Chip can bind CD38 with?an?affinity?constant?of?5.429 nM as determined?in a SPR assay(Routinely tested).
Endotoxin Level	< 1.0 EU/μg of the protein as determined by the LAL method.
Purity	SDS-PAGE: 99.3%; SEC-HPLC: 98.5%
Description	CD38 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.3 kDa and the accession number is P28907-1.
Reference	Ho IC,et al.(2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.,Matesanz-Isabel J,et al.(2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.,Zola H,et al.(2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
URL	https://www.targetmol.com/recombinant-protein/cd38_protein_human_recombinant_ecd_his_tag_

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