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タンパク質カタログ
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- サプライヤー
- TargteMol
- カタログNo.
- TMPY-00915
- 製品名称
- Serpin A1 Protein, Human, Recombinant (His)
- タンパク質名
- Serpin A1
- Species
- Human
- HOST
- HEK293 Cells
- 100μg: -
- お問い合わせ
Overview
| Synonyms | PRO2275, SerpinA1, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1, serpin peptidase inhibitor, clade A (α-1 antiproteinase, antitrypsin), member 1, α1AT, AAT, MGC9222, MGC23330, A1A, alpha1AT, A1AT, PI1, PI |
|---|---|
| Characteristics | Measured by its ability to inhibit trypsin cleavage of a fluorogenic peptide substrate, Mca-RPKPVE-Nval-WRK(Dnp)-NH2. The IC50 value is < 3.0 nM, as measured in 100μL reaction mixture containing 1.25 ng trypsin, 10 μM substrate, 50 mM Tris, 10 mM CaCl2, 0.15 M NaCl, pH 7.5. |
| Endotoxin Level | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Purity | 99.40% |
| Description | Serpin A1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.7 kDa and the accession number is P01009-1. |
| Reference | Camelier AA,et al.(2008) Alpha-1 antitrypsin deficiency: diagnosis and treatment. J Bras Pneumol. 34(7): 514-27.,Kilty SJ,et al.(2010) Polymorphisms in the SERPINA1 (Alpha-1-Antitrypsin) gene are associated with severe chronic rhinosinusitis unresponsive to medical therapy. Am J Rhinol Allergy. 24(1): e4-9.,Subramaniyam D,et al.(2010) Cholesterol rich lipid raft microdomains are gateway for acute phase protein, SERPINA1. Int J Biochem Cell Biol. 42(9): 1562-70.,Khnlein T,et al.(2008) Alpha-1 antitrypsin deficiency: pathogenesis, clinical presentation, diagnosis, and treatment. Am J Med. 121(1): 3-9. |
| URL | https://www.targetmol.com/recombinant-protein/serpina1_protein_human_recombinant_his_tag_ |
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