検索タンパク質、抗体、アッセイキット
タンパク質カタログ
輸入に関する法規制チェックは、御見積のご依頼をいただいた際に行います。
法規制によっては、定価として記載の価格に追加の費用が発生する場合や供給出来ない場合がございますので、あらかじめご了承ください。
- サプライヤー
- TargteMol
- カタログNo.
- TMPY-00876
- 製品名称
- Legumain Protein, Mouse, Recombinant (His)
- タンパク質名
- Legumain
- Species
- Mouse
- HOST
- HEK293 Cells
- 50μg: -
- お問い合わせ
Overview
| Synonyms | AI746452, AEP, AU022324, Prsc1, legumain |
|---|---|
| Characteristics | Measured by its ability to cleave the fluorogenic peptide substrate, N-carbobenzyloxy-Ala-Ala-Asn-7-amido-4-methyl coumarin(Z-AAN-AMC). The specific activity is > 350 pmoles/min/μg. (Activation description: The enzyme achieves its activity under acidic pH) |
| Endotoxin Level | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Purity | 97.80% |
| Description | Legumain Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 49.8 kDa and the accession number is A2RTI3. |
| Reference | Gawenda J,et al.(2007) Legumain expression as a prognostic factor in breast cancer patients. Breast Cancer Res Treat. 102(1): 1-6.,Clerin V,et al.(2007) Expression of the cysteine protease legumain in vascular lesions and functional implications in atherogenesis. Atherosclerosis. 201(1): 53-66.,Lew?“n S,et al.(2008) A Legumain-based minigene vaccine targets the tumor stroma and suppresses breast cancer growth and angiogenesis. Cancer Immunol Immunother. 57(4): 507-15.,Murthy RV,et al.(2005) Legumain expression in relation to clinicopathologic and biological variables in colorectal cancer. Clin Cancer Res. 11(6): 2293-9.,Schwarz G,et al.(2002) Characterization of legumain. Biol Chem. 383(11): 1813-6.,Liu C,et al.(2003) Overexpression of legumain in tumors is significant for invasion/metastasis and a candidate enzymatic target for prodrug therapy. Cancer Res. 63(11): 2957-64. |
| URL | https://www.targetmol.com/recombinant-protein/legumain_protein_mouse_recombinant_his_tag_hplc_verified |
お問い合わせリスト