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- サプライヤー
- TargteMol
- カタログNo.
- TMPY-00853
- 製品名称
- IL-1RA Protein, Human, Recombinant
- タンパク質名
- IL-1RA
- Species
- Human
- HOST
- E. coli
- 100μg: -
- お問い合わせ
Overview
| Synonyms | IL-1RN, IL1F3, interleukin 1 receptor antagonist, ICIL-1RA, IL-1ra3, MVCD4, IRAP, IL-1ra, DIRA, IL1RA |
|---|---|
| Characteristics | 1. Measured by its binding ability in a functional ELISA. Immobilized human IL1RA at 10 μg/ml (100 μl/well) can bind human IL1R2-Fc , The EC50 of human IL1R2-Fc is 0.04-0.1 μg/mL. 2. Measured by its binding ability in a functional ELISA. Immobilized human IL1RA at 10 μg/ml (100 μl/well) can bind human IL1R1-Fc , The EC50 of human IL1R1-Fc is 0.08-0.2 μg/mL. 3. Measured by its ability to induce Interferon gamma secretion by human natural killer lymphoma NK-92 cells in the presence of 250pg/mL IL1a. The EC50 for this effect is typically 3-12 ng/mL. |
| Endotoxin Level | Please contact us for more information. |
| Purity | 97.90% |
| Description | IL-1RA Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.3 kDa and the accession number is P18510-1. |
| Reference | El-Omar EM,et al. (2000) Interleukin-1 polymorphisms associated with increased risk of gastric cancer. Nature. 404 (6776): 398-402.,Langdahl BL,et al. (2000) Osteoporotic fractures are associated with an 86-base pair repeat polymorphism in the interleukin-1--receptor antagonist gene but not with polymorphisms in the interleukin-1beta gene. J Bone Miner. 15 (3): 402-14.,Steinkasserer A,et al. (1992) The human IL-1 receptor antagonist gene (IL1RN) maps to chromosome 2q14-q21, in the region of the IL-1 alpha and IL-1 beta loci. Genomics. 13 (3): 654-7. |
| URL | https://www.targetmol.com/recombinant-protein/il1ra_protein_human_recombinant |
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