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- サプライヤー
- TargteMol
- カタログNo.
- TMPY-00836
- 製品名称
- IGFBP-4 Protein, Human, Recombinant (His)
- タンパク質名
- IGFBP-4
- Species
- Human
- HOST
- HEK293 Cells
- 100μg: -
- お問い合わせ
Overview
| Synonyms | HT29-IGFBP, IBP4, BP-4, IGFBP-4, insulin-like growth factor binding protein 4 |
|---|---|
| Characteristics | 1. Measured by its ability to bind human IGF1 in functional ELISA. 2. Measured by its ability to bind human IGF2 in functional ELISA. 3. Measured by its ability to inhibit the biological activity of IGFI or IGFII on MCF7 human breast adenocarcinoma cells (Karey, K.P. et al. (1988) Cancer Research 48:4083.). The ED50 for this effect is typically 0.04-0.4 μg/mL in the presence of 14 ng/mL human IGFII. |
| Endotoxin Level | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Purity | 94.80% |
| Description | IGFBP-4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.4 kDa and the accession number is A0A024R1U8. |
| Reference | Wang J,et al.(1998) Overexpression of insulin-like growth factor-binding protein-4 (IGFBP-4) in smooth muscle cells of transgenic mice through a smooth muscle alpha-actin-IGFBP-4 fusion gene induces smooth muscle hypoplasia. Endocrinology. 139(5): 2605-14.,Chernausek SD,et al.(1995) Proteolytic cleavage of insulin-like growth factor binding protein 4 (IGFBP-4). Localization of cleavage site to non-homologous region of native IGFBP-4. J Biol Chem. 1995 May 12;270(19):11377-82. |
| URL | https://www.targetmol.com/recombinant-protein/igfbp4_protein_human_recombinant_his_tag_ |
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